Alun Wyn Jones returns to captain Wales for their final Rugby World Cup warm-up fixture against Ireland in a starting line-up featuring 15 changes.
Coach Warren Gatland has opted to make wholesale alterations for the fixture in Dublin following last weekend's 22-17 defeat against the same opponents in Cardiff.
Skipper Jones is joined by fellow powerhouse forwards Ross Moriarty and Justin Tipuric, while Aaron Wainwright makes up the back-row.
Rhys Patchell impressed enough off the bench against Ireland last time out to earn a place on the plane to Japan and is named at fly-half, with Tomos Williams starting at nine.
An exciting backline sees Hadleigh Parkes link up with Jonathan Davies at centre, while Josh Adams, George North and Leigh Halfpenny make up Wales' back three.
"This is our final preparation match so it is important we get enough rugby into us, get rugby ready ahead of our opener against Georgia which is just over two weeks away," said Gatland, whose squad depart for Japan on Wednesday.
"It is important we hit the ground running in Japan and we give the players enough time on the field.
"Saturday is the first time these players would have taken to the field as members of the World Cup squad, it has been a big week and it is a big opportunity for players to put their hand up and secure spots for the starting XV in Japan."
Wales team to face Ireland: Leigh Halfpenny, George North, Jonathan Davies, Hadleigh Parkes, Josh Adams, Rhys Patchell, Tomos Williams; Wyn Jones, Elliot Dee, Tomas Francis, Jake Ball, Alun Wyn Jones, Aaron Wainwright, Aaron Wainwright, Justin Tipuric, Ross Moriarty
Replacements: Ken Owen, Nicky Smith, Dillon Lewis, Adam Beard, Josh Navidi, Gareth Davies, Dan Biggar, Liam Williams