Sebastian Cancelliere and Emiliano Boffelli each scored two tries apiece as the Jaguares wrapped up a deserved win against the Sharks.
The Jaguares completed a comfortable 34-7 Super Rugby victory over the Sharks in Buenos Aires on Saturday.
Gonzalo Quesada's side, who lead the South African Conference, were inspired by the try-scoring exploits of Sebastian Cancelliere and Emiliano Boffelli in a dominant display.
Cancelliere touched down to cap a fine team move inside the opening three minutes, with Boffelli getting in on the act before the interval.
The hosts took the game beyond the Sharks before the hour mark as Boffelli plucked the ball from the sky before crossing the whitewash, while Cancelliere also doubled his tally soon after.
A late Andre Esterhuizen try provided some consolation for the Sharks, but an impressive Jaguares outfit had the final say courtesy of Santiago Carreras' score.
Robert du Preez's men remain bottom of the South African Conference.