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Quarter-finals
RC Toulon Vs London Irish at Stade Félix Mayol 8th May 2022![RC Toulon]()
RC Toulon
19 18Sun, May 8![London Irish]()
London Irish
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Lyon Vs Glasgow Warriors at Matmut Stadium, Gerland 7th May 2022
![Lyon]()
Lyon
35 27Sat, May 7![Glasgow Warriors]()
Glasgow
Semi-finals
Lyon Vs Wasps at Matmut Stadium, Gerland 14th May 2022![Lyon]()
Lyon
20 18Sat, May 14![Wasps]()
Wasps
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Edinburgh Rugby Vs Wasps at Hive Stadium 7th May 2022
![Edinburgh Rugby]()
Edinburgh
30 34Sat, May 7![Wasps]()
Wasps
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Gloucester Rugby Vs Saracens at Kingsholm 6th May 2022
![Gloucester Rugby]()
Gloucester
15 44Fri, May 6![Saracens]()
Saracens
RC Toulon Vs Saracens at Stade Félix Mayol 14th May 2022![RC Toulon]()
RC Toulon
25 16Sat, May 14![Saracens]()
Saracens
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Final
Lyon Vs RC Toulon at Stade Vélodrome 27th May 2022![Lyon]()
Lyon
30 12Fri, May 27![RC Toulon]()
RC Toulon
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| P | W | L | D | P +/- | Diff | Try +/- | TB | LB | Points | |
|---|---|---|---|---|---|---|---|---|---|---|
 Newcastle Red Bulls |
4 | 3 | 1 | 0 | 73 / 89 | -16 | 0 / 0 | 0 | 0 | 14 |
 RC Toulon |
4 | 3 | 1 | 0 | 107 / 57 | 50 | 0 / 0 | 0 | 1 | 11 |
 Biarritz Olympique |
4 | 2 | 1 | 1 | 59 / 47 | 12 | 0 / 0 | 0 | 1 | 11 |
 Worcester Warriors |
4 | 1 | 2 | 1 | 85 / 91 | -6 | 0 / 0 | 0 | 1 | 7 |
 Zebre Parma |
4 | 0 | 4 | 0 | 75 / 115 | -40 | 0 / 0 | 0 | 1 | 1 |
| P | W | L | D | P +/- | Diff | Try +/- | TB | LB | Points | |
 Lyon |
4 | 4 | 0 | 0 | 122 / 57 | 65 | 0 / 0 | 0 | 0 | 16 |
 Gloucester Rugby |
4 | 3 | 1 | 0 | 161 / 84 | 77 | 0 / 0 | 0 | 1 | 13 |
 Benetton Rugby |
4 | 2 | 2 | 0 | 75 / 95 | -20 | 0 / 0 | 0 | 0 | 8 |
 Perpignan |
4 | 1 | 3 | 0 | 54 / 138 | -84 | 0 / 0 | 0 | 0 | 4 |
 Dragons RFC |
4 | 0 | 4 | 0 | 74 / 112 | -38 | 0 / 0 | 0 | 2 | 2 |
| P | W | L | D | P +/- | Diff | Try +/- | TB | LB | Points | |
 Edinburgh Rugby |
4 | 3 | 1 | 0 | 161 / 47 | 114 | 0 / 0 | 0 | 1 | 13 |
 London Irish |
4 | 2 | 1 | 1 | 78 / 82 | -4 | 0 / 0 | 0 | 0 | 10 |
 Saracens |
4 | 2 | 2 | 0 | 118 / 78 | 40 | 0 / 4 | 0 | 1 | 9 |
 Brive |
4 | 1 | 2 | 1 | 41 / 146 | -105 | 0 / 0 | 0 | 0 | 6 |
 Pau |
4 | 1 | 3 | 0 | 75 / 120 | -45 | 4 / 0 | 1 | 0 | 5 |
| P | W | L | D | P +/- | Diff | Try +/- | TB | LB | Points | |
|
London Irish |
1 | 1 | 0 | 0 | 64 / 27 | 37 | 0 / 0 | 0 | 0 | 4 |
|
Edinburgh Rugby |
1 | 1 | 0 | 0 | 41 / 19 | 22 | 0 / 0 | 0 | 0 | 4 |
|
RC Toulon |
1 | 1 | 0 | 0 | 36 / 17 | 19 | 0 / 0 | 0 | 0 | 4 |
|
Lyon |
1 | 1 | 0 | 0 | 31 / 17 | 14 | 0 / 0 | 0 | 0 | 4 |
 Wasps |
1 | 1 | 0 | 0 | 39 / 29 | 10 | 0 / 0 | 0 | 0 | 4 |
|
Gloucester Rugby |
1 | 1 | 0 | 0 | 31 / 21 | 10 | 0 / 0 | 0 | 0 | 4 |
 Glasgow Warriors |
1 | 1 | 0 | 0 | 27 / 17 | 10 | 0 / 0 | 0 | 0 | 4 |
|
Saracens |
1 | 1 | 0 | 0 | 40 / 33 | 7 | 0 / 0 | 0 | 0 | 4 |
 Cardiff Rugby |
1 | 0 | 1 | 0 | 33 / 40 | -7 | 0 / 0 | 0 | 1 | 1 |
|
Biarritz Olympique |
1 | 0 | 1 | 0 | 29 / 39 | -10 | 0 / 0 | 0 | 0 | 0 |
 Northampton Saints |
1 | 0 | 1 | 0 | 21 / 31 | -10 | 0 / 0 | 0 | 0 | 0 |
|
Newcastle Red Bulls |
1 | 0 | 1 | 0 | 17 / 27 | -10 | 0 / 0 | 0 | 0 | 0 |
|
Worcester Warriors |
1 | 0 | 1 | 0 | 17 / 31 | -14 | 0 / 0 | 0 | 0 | 0 |
|
Benetton Rugby |
1 | 0 | 1 | 0 | 17 / 36 | -19 | 0 / 0 | 0 | 0 | 0 |
 Bath Rugby |
1 | 0 | 1 | 0 | 19 / 41 | -22 | 0 / 0 | 0 | 0 | 0 |
 Castres Olympique |
1 | 0 | 1 | 0 | 27 / 64 | -37 | 0 / 0 | 0 | 0 | 0 |
