Injured Wales pair Liam Williams and Scott Baldwin are absent from Warren Gatland's 32-man squad for their final Six Nations fixture in France on Saturday.
Full-back Williams sustained a shoulder injury in Saturday's 29-17 win over Italy in Rome – the first victory of a troubled campaign for Wales.
Hooker Baldwin, meanwhile, suffered a pectoral problem in Italy and will join Williams on the sidelines, with his Ospreys team-mate Sam Parry being called up to the squad.
Keiran Williams has also been released from the squad after sustaining a groin injury while featuring for the Ospreys earlier this month.
Wales are training in Nice ahead of their trip to the Stade de France, with the team announcement scheduled for Thursday.
Opponents France retain a slim chance of defending their title, but they need to post a bonus-point victory over Wales before hoping Ireland are on the receiving end of an upset at home to England.
Full Wales squad:
Forwards: Rhys Carre, Wyn Jones, Gareth Thomas, Ken Owens, Sam Parry, Bradley Roberts, Leon Brown, Tomas Francis, Dillon Lewis, Adam Beard, Rhys Davies, Dafydd Jenkins, Alun Wyn Jones, Jac Morgan, Tommy Reffell, Justin Tipuric, Aaron Wainwright, Taulupe Faletau.
Backs: Kieran Hardy, Rhys Webb, Tomos Williams, Dan Biggar, Rhys Patchell, Owen Williams, Mason Grady, Joe Hawkins, George North, Nick Tompkins, Josh Adams, Rio Dyer, Leigh Halfpenny, Louis Rees-Zammit.